Table 4 Results of Overall Survival Analysis by Cox Proportional Hazards Model for the untreated subgroup

HR (95 % CI)

P-value

HR (95 % CI)

P-value

High vs. Low

2.14 (1.05, 4.58)

0.0445

3.80 (1.58, 9.97)

0.0052

Positive vs. Negative

1.59 (0.43, 4.31)

0.4234

1.35 (0.34, 4.02)

0.6376

≥2 cm vs. <2 cm

2.05 (1.01, 4.22)

0.0508

1.41 (0.62, 3.23)

0.4178

Negative vs. Positive

1.62 (0.68, 3.51)

0.2504

0.99 (0.36, 2.51)

0.9863

Positive vs. Negative

2.84 (1.27, 7.05)

0.0173

NA^b

NA^b

Grade 2-3 vs. Grade 1

2.61 (1.09, 7.43)

0.0505

1.85 (0.67, 5.84)

0.2719

ND vs. Grade 1

1.46 (0.39, 5.23)

0.5667

1.34 (0.33, 5.03)

0.6763

Present vs. Absent

2.11 (0.81, 4.75)

0.0993

1.63 (0.54, 4.16)

0.3537

≥50 vs. <50

2.41 (1.03, 6.77)

0.0666

3.03 (1.17, 9.11)

0.0348