|
Prognostic Factor
|
Univariate (n = 403)
|
Multivariate (n = 360c)
|
|---|
| |
HR (95 % CI)
|
P-value
|
HR (95 % CI)
|
P-value
|
|
Menacalc
|
| |
High vs. Low
|
1.84 (1.08, 3.14)
|
0.0248
|
2.18 (1.19, 4.00)
|
0.0199
|
|
Her2a
|
| |
Positive vs. Negative
|
1.71 (0.77, 3.79)
|
0.1855
|
1.43 (0.58, 3.53)
|
0.4341
|
|
Tumor Size
|
| |
≥2 cm vs. <2 cm
|
1.40 (0.83, 2.35)
|
0.2024
|
1.45 (0.80, 2.66)
|
0.2234
|
|
ERa
|
| |
Negative vs. Positive
|
1.18 (0.65, 2.13)
|
0.5858
|
1.09 (0.57, 2.08)
|
0.7952
|
|
PRa
|
| |
Positive vs. Negative
|
2.36 (1.32, 4.25)
|
0.0040
|
NAb
|
NAb
|
|
Histological grade
|
| |
Grade 2-3 vs. Grade 1
|
1.62 (0.82, 3.22)
|
0.1682
|
1.27 (0.59, 2.72)
|
0.5450
|
| |
ND vs. Grade 1
|
1.06 (0.33, 3.42)
|
0.9264
|
0.75 (0.22, 2.49)
|
0.6354
|
|
Lymphatic invasion
|
| |
Present vs. Absent
|
1.78 (0.97, 3.26)
|
0.0614
|
1.67 (0.85, 3.30)
|
0.1359
|
|
Treatment
|
| |
Yes vs. No
|
0.60 (0.35, 1.00)
|
0.0514
|
0.54 (0.29, 0.99)
|
0.0454
|
|
Age, years
|
| |
≥50 vs. <50
|
1.90 (1.06, 3.43)
|
0.0319
|
1.93 (1.02, 3.65)
|
0.0425
|
- aIHC marker
- bPR was not included as ER and PR are correlated
- cTumors excluded if missing data for either Her2 or ER
