Table 3 Results of Overall Survival Analysis by Cox Proportional Hazards Model for the full dataset

HR (95 % CI)

P-value

HR (95 % CI)

P-value

High vs. Low

1.84 (1.08, 3.14)

0.0248

2.18 (1.19, 4.00)

0.0199

Positive vs. Negative

1.71 (0.77, 3.79)

0.1855

1.43 (0.58, 3.53)

0.4341

≥2 cm vs. <2 cm

1.40 (0.83, 2.35)

0.2024

1.45 (0.80, 2.66)

0.2234

Negative vs. Positive

1.18 (0.65, 2.13)

0.5858

1.09 (0.57, 2.08)

0.7952

Positive vs. Negative

2.36 (1.32, 4.25)

0.0040

NA^b

NA^b

Grade 2-3 vs. Grade 1

1.62 (0.82, 3.22)

0.1682

1.27 (0.59, 2.72)

0.5450

ND vs. Grade 1

1.06 (0.33, 3.42)

0.9264

0.75 (0.22, 2.49)

0.6354

Present vs. Absent

1.78 (0.97, 3.26)

0.0614

1.67 (0.85, 3.30)

0.1359

Yes vs. No

0.60 (0.35, 1.00)

0.0514

0.54 (0.29, 0.99)

0.0454

≥50 vs. <50

1.90 (1.06, 3.43)

0.0319

1.93 (1.02, 3.65)

0.0425