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Fig. 4 | BMC Cancer

Fig. 4

From: APC selectively mediates response to chemotherapeutic agents in breast cancer

Fig. 4

MMTV-PyMT;ApcMin/+ cells have higher aldehyde dehydrogenase (ALDH) enzyme activity than MMTV-PyMT;Apc+/+ cells. ALDH activity was measured using an Aldefluor™ Kit. For each cell line a Control (+DEAB) and test (−DEAB) sample were run. a Representative FACS analysis of ALDH activity in MMTV-PyMT;Apc+/+ and MMTV-PyMT;ApcMin/+ cells using the Aldefluor™ assay. ALDH activity is increased in MMTV-PyMT;ApcMin/+ cells. b The population of cells that shifted outside of the control population was calculated for each test sample, indicating ALDH activity. MMTV-PyMT;ApcMin/+cells show a larger percentage of cells shifted outside of the control range than MMTV-PyMT;Apc+/+cells. Data are shown as the means ± SEM from 3 independent experiments; *P < 0.05

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