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Fig. 1 | BMC Cancer

Fig. 1

From: Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinoma

Fig. 1

Representative FISH data showing MAPK7 gene amplification in NSCLC and sqEC tumor tissues. FISH probes were generated for MAPK7 (red) and internal CEP17 control (green) genes. MAPK7 non-amplified tumor tissue is represented by image LC016, while MAPK7 amplified lung and esophageal tumor tissues are shown in images LC035 and EC012, respectively. Gene amplification criteria were defined as a MAPK7/CEP17 ratio of >2 across at least tumor 50 cells

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