Fig. 1From: Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinomaRepresentative FISH data showing MAPK7 gene amplification in NSCLC and sqEC tumor tissues. FISH probes were generated for MAPK7 (red) and internal CEP17 control (green) genes. MAPK7 non-amplified tumor tissue is represented by image LC016, while MAPK7 amplified lung and esophageal tumor tissues are shown in images LC035 and EC012, respectively. Gene amplification criteria were defined as a MAPK7/CEP17 ratio of >2 across at least tumor 50 cellsBack to article page