Fig. 5From: A small molecular agent YL529 inhibits VEGF-D-induced lymphangiogenesis and metastasis in preclinical tumor models in addition to its known antitumor activitiesEffects of YL529 on tumor growth, lung and lymph node metastasis in muscle model. The muscle metastasis models were treated with YL529 or controls orally. a YL529 resulting in significant tumor growth inhibition; b There was no significant difference of body weight after YL529 treated; c and d Percentage of mice with lung and lymph node metastasis; e Mean volume of auxiliary lymph nodes were harvested from mice. Mean ± SEM, n = 10, *p < 0.05, **p < 0.01Back to article page