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Table 6 Estimation of the hazard ratio for overall survival

From: Lymph node density as a prognostic variable in node-positive bladder cancer: a meta-analysis

Study HR estimation Co-factors Analysis results
Osawa [19] HR, 95 % CI Histology, no. of positive LNs, adjuvant chemotherapy Significant
Guzzo [22] HR, 95 % CI Age, sex, diversion type, pT stage, adjuvant chemotherapy Not significant
Stephenson [23] HR, 95 % CI pT stage, aggregate LN metastasis diameter, lymphovascular invasion, margin status, extracapsular extension Not significant
Morgan [26] HR, 95 % CI Age, Charlson comorbidity index, pT stage, tumor grade, no. of LNs removed, adjuvant chemotherapy, diversion type, year of surgery, surgeon volume, transfusion Significant
Mmeje [29] P value, event no. (univariate) - Not significant
  1. HR: hazard ratio, CI: confidence interval, LN: lymph node