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Table 6 Estimation of the hazard ratio for overall survival

From: Lymph node density as a prognostic variable in node-positive bladder cancer: a meta-analysis

Study

HR estimation

Co-factors

Analysis results

Osawa [19]

HR, 95 % CI

Histology, no. of positive LNs, adjuvant chemotherapy

Significant

Guzzo [22]

HR, 95 % CI

Age, sex, diversion type, pT stage, adjuvant chemotherapy

Not significant

Stephenson [23]

HR, 95 % CI

pT stage, aggregate LN metastasis diameter, lymphovascular invasion, margin status, extracapsular extension

Not significant

Morgan [26]

HR, 95 % CI

Age, Charlson comorbidity index, pT stage, tumor grade, no. of LNs removed, adjuvant chemotherapy, diversion type, year of surgery, surgeon volume, transfusion

Significant

Mmeje [29]

P value, event no. (univariate)

-

Not significant

  1. HR: hazard ratio, CI: confidence interval, LN: lymph node