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Table 4 Estimation of the hazard ratio for disease-free survival

From: Lymph node density as a prognostic variable in node-positive bladder cancer: a meta-analysis

Study

HR estimation

Co-factors

Analysis results

Fleischmann [18]

HR, 95 % CI

Extracapsular extension, no. of positive LNs

Not significant

Guzzo [22]

HR, 95 % CI

Age, sex, diversion type, pT stage, adjuvant chemotherapy

Not significant

Jensen [25]

HR, 95 % CI

Age, sex, pT stage, pN stage, metasis above the aortic bifurcation, extracapsular extension, volume dependent LN density, diameter of largest LN, volume of metastatic LNs

Not significant

Masson-Lecomte [28]

HR, 95 % CI

pT stage, lymphovascular invasion, extracapsular extension, adjuvant chemoethrapy

Significant

Mmeje [29]

P value, event no. (univariate)

-

Not significant

Kwon [30]

HR, 95 % CI

pT stage, pN stage, no. of positive LNs, adjuvant chemotherapy

Not significant

  1. HR: hazard ratio, CI: confidence interval, LN: lymph node