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Table 3 Pathologic characteristics from the eligible studies

From: Lymph node density as a prognostic variable in node-positive bladder cancer: a meta-analysis

Study Tumor grade (G0/G1/G2/G3) Pathologic T stage (pT0/is/a/1/2/3/4) Pathologic N stage (pN1/2/3) Median no. of LNs removed, range Median no. of positive LNs, range Median LN density, range (%)
Herr [5] NA 79 (≤T2)/123/0 54/87/21 13 (2–32) 3.3 NA
Fleischmann [18] NA 0/0/0/19 (T1/2)/53/30 32/69/0 22 (10–43) NA NA
Osawa [19] 0/0/9/51 0/0/0/1/6/38/15 21/39 12 (1–80) 2 (1–12) 23.1 (1.3-100)
Wiesner [20] 0/0/8/38 0/0/0/3/11/24/8 NA 33 (15–77) 3 (1–28) 11 (1–73)
Furukawa [21] 0/0/12/70 0/0/0/0/19/37/26 32/50/0 14.4 (mean) (6–37) 3.1 (mean) (1–12) 25.3 (2.8–100)
Guzzo [22] NA 9 (≤T1)/13/63 (T3/4) NA 16.7 (mean) (5–56) NA NA
Stephenson [23] NA 107 (≤T2)/27 (T3/4) 62/72 (N2/3) 14 (IQR: 9–20) 2 (IQR: 1–3) 17 (IQR: 9–38)
May [24] 79 (≤G2)/398 24 (≤T1)/103/350 (T3/4) 187/290/0 12 (1–66) 2 (1–25) 17.6 (2.3–100)
Jensen [25] NA NA 16/9/18 NA NA NA
Morgan [26] 27 (LG)/741 (HG) 14 (≤T1)/48/131/585 NA 9 (IQR: 4–16) 2 (IQR: 1–3) 25 (IQR: 13–50)
Kassouf [27] NA 65 (≤T1)/176/505/292 NA 18 (IQR: 11–32) 2 (IQR: 1–5) 14.3 (IQR: 6.7–33.3)
Masson-Lecomte [28] NA 0/0/0/2/15/39/19 10/10/6 18 (3–49) 3 (1–35) 19 (2–100)
Mmeje [29] NA 0/1/0/2/13/26/7 NA 19 (mean) (5–35) 3 (mean) (1–12) NA
Kwon [30] NA NA 62/116/1 16 (1–118) 3 (1–37) 17.6 (2.6–100)
  1. LV: lymph node, NA: not available, IQR: interquartile range, LG: low grade, HG: high grade