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Table 2 Patient characteristics from the eligible studies

From: Lymph node density as a prognostic variable in node-positive bladder cancer: a meta-analysis

Study No. of patients Median age, range (years) Gender (male/female) Upper limit of PLND Neoadjuvant chemotherapy Adjuvant chemotherapy Median Follow-up, range (months)
Herr [5] 162 67 (36–87) NA Distal common iliac artery 0 NA 90 (24–180)
Fleischmann [18] 101 67 (35–89) 87/14 Crossing of the ureter with common iliac artery 0 41 21 (1–191)
Osawa [19] 60 68 (34–84) 48/12 Below the bifurcation of common iliac artery (almost) Above iliac bifurcation (a few) 0 25 41 (4–138)
Wiesner [20] 46 NA NA Inferior mesenteric artery 0 27 22 (1–76)
Furukawa [21] 82 70.3 (42–86) 62/20 Distal common iliac artery 0 17 33.6 (mean) (2–142)
Guzzo [22] 85 NA 67/18 Bifurcation of common iliac artery 0 55 46 (3–223)
Stephenson [23] 134 68 (IQR: 59–75) NA Distal common iliac artery 0 90 23 (IQR: 10–36)
May [24] 477 66.3 (33–86) 376/101 NA 0 159 16
Jensen [25] 43 NA NA Inferior mesenteric artery 0 0 53 (24–83)
Morgan [26] 779 NA 530/249 NA 28 296 NA
Kassouf [27] 1,038 67 (IQR: 60–73) 821/217 Not standardized 0 NA 33 (IQR: 14–69)
Masson-Lecomte [28] 75 65 (31–85) 64/11 Common iliac bifurcation NA 46 40.6 (3–127)
Mmeje [29] 50 69 (mean) (50–83) 38/12 Aortic bifurcation 29 19 39.6 (16–75)
Kwon [30] 179 NA NA Not standardized 0 NA 64.3 (1–231.4)
  1. PLND: pelvic lymph node dissection, NA: not available, IQR: interquartile range