Table 2 Patient characteristics from the eligible studies
From: Lymph node density as a prognostic variable in node-positive bladder cancer: a meta-analysis
Study | No. of patients | Median age, range (years) | Gender (male/female) | Upper limit of PLND | Neoadjuvant chemotherapy | Adjuvant chemotherapy | Median Follow-up, range (months) |
|---|---|---|---|---|---|---|---|
Herr [5] | 162 | 67 (36–87) | NA | Distal common iliac artery | 0 | NA | 90 (24–180) |
Fleischmann [18] | 101 | 67 (35–89) | 87/14 | Crossing of the ureter with common iliac artery | 0 | 41 | 21 (1–191) |
Osawa [19] | 60 | 68 (34–84) | 48/12 | Below the bifurcation of common iliac artery (almost) Above iliac bifurcation (a few) | 0 | 25 | 41 (4–138) |
Wiesner [20] | 46 | NA | NA | Inferior mesenteric artery | 0 | 27 | 22 (1–76) |
Furukawa [21] | 82 | 70.3 (42–86) | 62/20 | Distal common iliac artery | 0 | 17 | 33.6 (mean) (2–142) |
Guzzo [22] | 85 | NA | 67/18 | Bifurcation of common iliac artery | 0 | 55 | 46 (3–223) |
Stephenson [23] | 134 | 68 (IQR: 59–75) | NA | Distal common iliac artery | 0 | 90 | 23 (IQR: 10–36) |
May [24] | 477 | 66.3 (33–86) | 376/101 | NA | 0 | 159 | 16 |
Jensen [25] | 43 | NA | NA | Inferior mesenteric artery | 0 | 0 | 53 (24–83) |
Morgan [26] | 779 | NA | 530/249 | NA | 28 | 296 | NA |
Kassouf [27] | 1,038 | 67 (IQR: 60–73) | 821/217 | Not standardized | 0 | NA | 33 (IQR: 14–69) |
Masson-Lecomte [28] | 75 | 65 (31–85) | 64/11 | Common iliac bifurcation | NA | 46 | 40.6 (3–127) |
Mmeje [29] | 50 | 69 (mean) (50–83) | 38/12 | Aortic bifurcation | 29 | 19 | 39.6 (16–75) |
Kwon [30] | 179 | NA | NA | Not standardized | 0 | NA | 64.3 (1–231.4) |