Skip to main content

Table 1 Prognostic clinicopathologic variables as predictors of disease-specific survival in 335 NSCLC-patients

From: Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival

Characteristics

Patients N, (%)

Median survival (months)

5-year survival (%)

P

Age

   

.421

≤65 years

156 (47)

98

56

 

>65 years

179 (53)

NR

60

 

Sex

   

.220

Female

82 (24)

190

64

 

Male

253 (76)

98

56

 

Smoking status

   

.257

Never

15 (5)

19

43

 

Previous

105 (31)

84

55

 

Present

215 (64)

NR

60

 

Performance status

   

.016

0

197 (59)

NR

63

 

1

120 (36)

64

52

 

2

18 (5)

25

33

 

Weight loss

   

.759

<10 %

303 (90)

190

58

 

>10 %

32 (10)

98

57

 

Histology

   

.028

Squamous cell carcinoma

191 (57)

NR

66

 

Adenocarcinoma

113 (34)

54

46

 

Large cell carcinoma

31 (9)

98

56

 

Differentiation

   

<.001

Poor

138 (41)

47

47

 

Moderate

144 (43)

190

65

 

Well

53 (16)

NR

68

 

Surgical procedure

   

0.007

Wedge + Lobectomy

243 (73)

190

62

 

Pneumectomy

92 (27)

37

47

 

Pathological stage

   

<.001

pI

157 (47)

NR

72

 

pII

136 (41)

62

51

 

pIIIA

42 (12)

17

24

 

Tumor stage

   

<.001

1

85 (25)

190

75

 

2

188 (56)

84

57

 

3

62 (19)

25

37

 

Nodal stage

   

<.001

0

232 (69)

NR

67

 

1

76 (23)

35

43

 

2

27 (8)

18

18

 

Surgical margins

   

.374

Free

307 (92)

190

59

 

Not free

28 (8)

47

48

 

Vascular infiltration

   

<.001

No

284 (85)

190

62

 

Yes

51 (15)

27

33

 
  1. NR, not reached; NCSLC, non-small cell lung cancer