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Fig. 2 | BMC Cancer

Fig. 2

From: MicroRNA-217 functions as a prognosis predictor and inhibits colorectal cancer cell proliferation and invasion via an AEG-1 dependent mechanism

Fig. 2

MiR-217 inhibits the growth of CRC cell lines in vitro and in vivo. (a) The relative expression level of miR-217 when transfected with miR-217 mimics and mimics NC measured by qRT-PCR. The average miRNA expression from mimics NC was appointed as 1. (b) The proliferation curve of SW480 and SW620 cells after transfected with miR-217 mimics by CCK8 assay. (c) Assessment of colony formation when upregulation of miR-217 expression. (d) The effects of overexpression of miR-217 on xenograft tumor growth in mice. Tumor growth curves were drew by measuring the subcutaneous tumor volumes every 4 days. Data are presented as mean ± SD. (e) Relative miR-217 expression level in excised tumors. *P < 0.05, **P < 0.01

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