The role of the REG4 gene and its encoding product in ovarian epithelial carcinoma

BMC Cancer

Table 1 REG4 protein expression during ovarian epithelial carcinogenesis

Groups	n	REG4 protein expression
Groups	n	−	+	++	+++	PR (%)
Normal ovarian tissue	26	20	2	2	2	23.1*
Benign ovarian tumor	10	3	2	1	4	70.0
Borderline ovarian tumor	22	4	2	2	14	81.8**
Ovarian cancer	235	116	45	41	33	50.6
Metastatic cancer in omentum	44	17	9	12	6	61.4
Groups	n	REG4 protein expression
Groups	n	−	+	++	+++	PR (%)
Primary ovarian cancer	34	7	9	10	8	79.4^#
Metastatic cancer in omentum	34	12	9	10	3	64.7

PR, positive rate
*P < 0.05 (normal ovarian tissue compared with benign tumor and primary carcinoma)
**P < 0.01 (ovarian borderline tumor compared with normal ovarian tissue)
^#P = 0.076 (metastatic lesions compared with relative primary cancer tissues)

ISSN: 1471-2407