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Fig. 4 | BMC Cancer

Fig. 4

From: The role of the REG4 gene and its encoding product in ovarian epithelial carcinoma

Fig. 4

Relationship between REG4 mRNA expression and clinicopathological features of ovarian cancer. REG4 mRNA expression was quantified by real-time RT-PCR in normal ovarian tissue (No; n = 17), benign (Be; n = 10) and borderline (Bo; n = 6) tumors, primary (Ca; n = 66) and metastatic cancers in the omentum (Om; n = 21). aREG4 mRNA expression levels are significantly higher in both benign ovarian tumors and primary carcinoma compared to normal ovarian tissue. b Mucinous (Mu) tumors show higher REG4 mRNA expression levels than serous (Se) tumors; and Mann-Whitney U test showed that REG4 mRNA expression is higher in well- and moderately-differentiated tumors than in poorly-differentiated tumors (c), but there was no significant difference between (d) FIGO staging I–II & III–IV; *P < 0.05

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