Fig. 2
Overall survival (ITT: intent-to-treat OS: overall survival-population: n = 77); (a) of the overall population (solid line), patients with a starting dose of 320 mg/m2 (broken line) and ≤ 280 mg/m2 (dotted line); (b) according to prognostic factors defined by Sonpavde et al.; overall survival is displayed according to the number of risk factors: 0 (orange), 1 (green), 2 (blue), 3/4 (red) risk factors; risk factors were: presence of liver metastasis, ECOG = 1, Hb value < 10 g/dL, time from prior chemotherapy < 6 months; RF: risk factor; ITT: intent-to-treat; OS: overall survival