Pegylated liposomal doxorubicin (Lipo-Dox®) combined with cyclophosphamide and 5-fluorouracil is effective and safe as salvage chemotherapy in taxane-treated metastatic breast cancer: an open-label, multi-center, non-comparative phase II study

Table 7 Change of left ventricular ejection fraction before and after treatment

Population	n	Baseline	After treatment	P valve
Evaluable cases	40	70.93 %	68.59 %	0.115
Patients with Cardiovascular history	18^a	69.89 %	66.36 %	0.2308^b
Previous exposure to anthracyclines
Yes	7	71.14 %	67.57 %	0.85
No	36	70.61 %	68.93 %	0.27

ISSN: 1471-2407