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Table 7 Change of left ventricular ejection fraction before and after treatment

From: Pegylated liposomal doxorubicin (Lipo-Dox®) combined with cyclophosphamide and 5-fluorouracil is effective and safe as salvage chemotherapy in taxane-treated metastatic breast cancer: an open-label, multi-center, non-comparative phase II study

Population n Baseline After treatment P valve
Evaluable cases 40 70.93 % 68.59 % 0.115
Patients with Cardiovascular history 18a 69.89 % 66.36 % 0.2308b
Previous exposure to anthracyclines     
Yes 7 71.14 % 67.57 % 0.85
No 36 70.61 % 68.93 % 0.27
  1. aExclude two subjects only have baseline record
  2. bWilcoxon test