Table 4 Relative risk (RR) of cancer in offspring according to maternal hyperemesis gravidarum (HG)- status for selected types of cancer combined and separately for the most common types according to age at diagnosis, with 95 % confidence intervals (95 % CI)
Cancer type | Age at diagnosis, in years | Crude RR (95 % CI) | Adjusted RR* (95 % CI)* |
|---|---|---|---|
All selected cancer forms | |||
n = 9.352 | 0–10 | 1.16 (0.90–1.51) | 1.18 (0.91–1.53) |
n = 5.453 | 11–20 | 1.21 (0.84–1.74) | 1.21 (0.84–1.74) |
Leukemia | |||
n = 4.114 | 0–10 | 1.07 (0.70–1.64) | 1.08 (0.71–1.65) |
n = 1.000 | 11–20 | 0.70 (0.25–1.93) | 0.70 (0.25–1.93) |
Central nervous system | |||
n = 3.003 | 0–10 | 1.18 (0.74–1.89) | 1.22 (0.76–1.94) |
n = 1.521 | 11–20 | 1.27 (0.63–2.56) | 1.27 (0.62–2.56) |
Lymphoma | |||
n = 491 | 0–10 | 0.95 (0.29–3.12) | 0.94 (0.28–3.10) |
n = 1.362 | 11–20 | 2.13 (1.14–3.99) | 2.08 (1.11–3.90) |
Nephroblastoma | |||
n = 422 | 0–10 | 2.02 (0.94–4.35) | 2.06 (0.95–4.45) |
n = 19 | 11–20 | – | – |