Skip to main content

Advertisement

Table 4 Relative risk (RR) of cancer in offspring according to maternal hyperemesis gravidarum (HG)- status for selected types of cancer combined and separately for the most common types according to age at diagnosis, with 95 % confidence intervals (95 % CI)

From: Hyperemesis gravidarum and risk of cancer in offspring, a Scandinavian registry-based nested case–control study

Cancer type Age at diagnosis, in years Crude RR (95 % CI) Adjusted RR* (95 % CI)*
All selected cancer forms
n = 9.352 0–10 1.16 (0.90–1.51) 1.18 (0.91–1.53)
n = 5.453 11–20 1.21 (0.84–1.74) 1.21 (0.84–1.74)
Leukemia
n = 4.114 0–10 1.07 (0.70–1.64) 1.08 (0.71–1.65)
n = 1.000 11–20 0.70 (0.25–1.93) 0.70 (0.25–1.93)
Central nervous system
n = 3.003 0–10 1.18 (0.74–1.89) 1.22 (0.76–1.94)
n = 1.521 11–20 1.27 (0.63–2.56) 1.27 (0.62–2.56)
Lymphoma
n = 491 0–10 0.95 (0.29–3.12) 0.94 (0.28–3.10)
n = 1.362 11–20 2.13 (1.14–3.99) 2.08 (1.11–3.90)
Nephroblastoma
n = 422 0–10 2.02 (0.94–4.35) 2.06 (0.95–4.45)
n = 19 11–20
  1. *Adjusted for maternal age and maternal country of birth