Fig. 3

Concordance in the clinical performance of methylation biomarkers between the self-collected and physician-collected groups. Receiver operating characteristic (ROC) curve analysis of PAX1, SOX1 and ZNF582. The area under curve (AUC) of the ROC curve of each gene was calculated for the diagnosis of CIN3 and further progressed (CIN3+) lesions. Differences with P-values less than 0.05 were considered to indicate statistical significance