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Table 2 EC50 (μM) values of DT320 for different cancer cell lines grown on Matrigel (fully malignant phenotype) vs SISgel (suppressed phenotype)

From: Identification of novel drugs to target dormant micrometastases

Cell line

Matrigel

SISgel

Ratio

p

MDA-MB-435 (breast)

48.2

20.0

2.4

<0.01

U251 (glioblastoma)

95.0

64.6

1.5

N.S.

DU145 (prostate)

183.2

45.7

4.0

<0.001

AGS (gastric)

104.4

45.1

2.3

<0.01