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Fig. 14 | BMC Cancer

Fig. 14

From: NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest

Fig. 14

Induced expression of NBPF1 in DLD1Tr21 cells does not result in a G1 cell cycle arrest or nuclear accumulation of p53. (A) Cell cycle distribution of DLD1Tr21/Mock and DLD1Tr21/NBPF1 cells in the absence or presence of dox (48 h) shows no G1 arrest upon NBPF1 expression. (B) Immunofluorescence for p53 revealed no increased accumulation in the nucleus upon NBPF1 expression. Expression of EGFP or NBPF1 (using antibody sc-82241) is induced upon treatment of the cells with dox for 48 h. Nuclei were visualized with DAPI. Scale bars: 10 μm

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BMC Cancer

ISSN: 1471-2407

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