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Table 3 Multivariate Cox regression for overall survival in patients with R0 resected T4 UICC II colorectal cancer. Patients over 80 years of age were excluded

From: Benefit of adjuvant chemotherapy in patients with T4 UICC II colon cancer

Variable

Value

p value

Hazard Ratio

lower 95 % CI

upper 95 % C

Chemotherapy

−CTX

 

1.00

  
 

+CTX

0.005

.041

0.22

0.76

Age at diagnosis (continuous)

 

0.086

1.03

0.99

1.06

Sex

Male

 

1.00

  
 

Female

0.275

0.75

0.44

1.26

Grading

G2

 

1.00

  
 

G3

<0.001

2.64

1.50

4.64

Lymphnodes examined

1–11

 

1.00

  
 

12–23

0.003

0.31

0.15

0.68

 

24+

0.003

0.26

0.11

0.64

 

Unknown

0.503

0.62

0.16

2.50

Lymph vessel invasion

LO

 

1.00

  
 

L1

0.573

1.22

0.62

2.39

 

LX

0.114

0.41

0.41

1.24

Vein invasion

VO

 

1.00

  
 

V1

0.714

0.86

0.37

1.97

 

VX

0.054

2.10

0.99

4.48