Fig. 5

Association of Cell surface GRP78 with α2M* induces invadopodia formation. QGY-7703 cells were treated with vehicle, α2M*, PP2 or PP2 in combination with α2M* and co-stained with TRITC-conjugated Phalloidin and anti-Cortactin antibody. The distribution of F-actin (red) and cortactin (green) was observed using a confocal microscope. The invadopodia was indicated as yellow patches. Scale Bar 25 μm