TY - JOUR AU - Zhao, Song AU - Li, Hongdan AU - Wang, Qingjun AU - Su, Chang AU - Wang, Guan AU - Song, Huijuan AU - Zhao, Liang AU - Luan, Zhidong AU - Su, Rongjian PY - 2015 DA - 2015/05/10 TI - The role of c-Src in the invasion and metastasis of hepatocellular carcinoma cells induced by association of cell surface GRP78 with activated α2M JO - BMC Cancer SP - 389 VL - 15 IS - 1 AB - Emerging data have suggested that cell surface GRP78 is a multifunctional receptor and has been linked to proliferative and antiapoptotic signaling cascades. Activated α2−macroglobin (α2M*) is a natural circulating ligand of cell surface GRP78. Association of cell surface GRP78 with α2M* is involved in the regulation of cell proliferation, survival and apoptosis in human cancers. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-015-1401-z DO - 10.1186/s12885-015-1401-z ID - Zhao2015 ER -