Fig. 1
From: Prognostic value of tumor suppressors in osteosarcoma before and after neoadjuvant chemotherapy
Representative images of immunohistochemistry of the six analyzed biomarkers. For each part (a–f) the same order of samples is shown: left (positive staining), middle (negative staining), right (positive staining of a lung metastasis). a, nuclear and cytoplasmic P16 staining. b, nuclear P53. c, cytoplasmic PTEN. d, nuclear maspin. e, nuclear Ki67. f, nuclear BMI1. Normalized magnification of all images, 40x; Hematoxylin counterstaining