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Table 3 Association results for the 10 candidate SNPs

From: Genome-wide association study of susceptibility loci for breast cancer in Sardinian population

A

      

SNP

corr

FREQ1 cases

FREQ1_CT

N

p-value

n.a. p-value*

rs857989

0.811

0.131

0.106

2866

3.99E-03

4.02E-03

rs11178748

0.824

0.083

0.079

2848

0.289

0.560

rs1903974

0.940

0.043

0.070

2837

5.94E-06

1.34E-05

rs1928482

0.895

0.351

0.313

2771

1.09E-03

2.24E-03

rs10979327

0.697

0.078

0.069

2840

0.178

0.220

rs17032957

0.651

0.749

0.748

2816

0.879

0.910

rs13393791

0.793

0.051

0.041

2847

0.093

0.068

rs6661074

0.806

0.474

0.434

2855

3.62E-03

2.23E-03

rs345299

0.885

0.477

0.530

2789

5.38E-05

9.05E-05

rs17633986

0.809

0.890

0.882

2822

0.553

0.331

B

      

MARKER

ALLELES

FREQ1_cases

FREQ1_CT

N

n.a. p-value*

 

rs857989

C/G

0.130

0.106

4469

8.02E-04

 

rs11178748

A/G

0.083

0.088

4432

0.499

 

rs1903974

A/G

0.044

0.063

4440

2.40E-04

 

rs1928482

C/T

0.350

0.319

4344

3.42E-03

 

rs10979327

G/T

0.078

0.074

4456

0.506

 

rs17032957

A/G

0.751

0.750

4414

0.865

 

rs13393791

C/T

0.050

0.045

4441

0.365

 

rs6661074

A/G

0.470

0.442

4416

0.010

 

rs345299

A/C

0.481

0.531

4343

1.16E-05

 

rs17633986

C/T

0.889

0.877

4451

0.100

 
  1. A. Results on Taqman genotypes for 1362 breast cancer cases and 1514 controls included in the GWAS.
  2. B. Results on Taqman genotypes for all 1563 breast cancer cases and 2981 controls.
  3. *n.a. p-value: not adjusted p-value, not corrected for population stratification.
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BMC Cancer

ISSN: 1471-2407

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