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Table 1 Tumor characteristics at the time of diagnosis, for 921 patients (all women) with sporadic, BRCA-mutation-negative breast cancer

From: Genome-wide association study of susceptibility loci for breast cancer in Sardinian population

Characteristic Patients, n (%)
Pathological TNM classification
 pT1-2 830 (90.1)
 pT3-4 91 (9.9)
 pN0 533 (57.9)
 pN1 388 (42.1)
 M0 751 (81.5)
 M1 43 (4.7)
 Mx 127 (13.8)
Receptor status
 ER- 234 (25.4)
 ER+ 687 (74.6)
 PR- 260 (28.2)
 PR+ 661 (71.8)
 HER2- 601 (65.3)
 HER2+ 174 (18.9)
 Not tested 146 (15.8)
Molecular subtypea
 ER+/PR+/HER2- 545 (70.3)
 ER+/PR+/HER2+ 142 (18.3)
 ER-/PR-/HER2+ 32 (4.1)
 Triple negative (ER-/PR-/HER2-) 56 (7.2)
  1. ER, estrogen receptor; PR, progesterone receptor.
  2. a For the 775 cases tested for all three receptor markers.