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Table 1 Tumor characteristics at the time of diagnosis, for 921 patients (all women) with sporadic, BRCA-mutation-negative breast cancer

From: Genome-wide association study of susceptibility loci for breast cancer in Sardinian population

Characteristic

Patients, n (%)

Pathological TNM classification

 pT1-2

830 (90.1)

 pT3-4

91 (9.9)

 pN0

533 (57.9)

 pN1

388 (42.1)

 M0

751 (81.5)

 M1

43 (4.7)

 Mx

127 (13.8)

Receptor status

 ER-

234 (25.4)

 ER+

687 (74.6)

 PR-

260 (28.2)

 PR+

661 (71.8)

 HER2-

601 (65.3)

 HER2+

174 (18.9)

 Not tested

146 (15.8)

Molecular subtypea

 ER+/PR+/HER2-

545 (70.3)

 ER+/PR+/HER2+

142 (18.3)

 ER-/PR-/HER2+

32 (4.1)

 Triple negative (ER-/PR-/HER2-)

56 (7.2)

  1. ER, estrogen receptor; PR, progesterone receptor.
  2. a For the 775 cases tested for all three receptor markers.