Figure 2
From: Autoantibodies in breast cancer sera are not epiphenomena and may participate in carcinogenesis

The three specimens depicted in A, DCIS, B, IDC, and C, BBD show a speckled pattern. The arrow in A shows a negative metaphase plate; the arrows in B show the negative unstained images of nucleoli while the arrow in C shows a positive metaphase plate suggesting a mixed homogeneous and speckled pattern.