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Figure 8 | BMC Cancer

Figure 8

From: High-recovery visual identification and single-cell retrieval of circulating tumor cells for genomic analysis using a dual-technology platform integrated with automated immunofluorescence staining

Figure 8

Whole exome sequencing of SKBR3 mCTCs. The chromosomal region containing the p.R175H mutation in TP53 is shown from whole genome amplification products from 8 individual cells and a pool of 5 cells that were picked from a slide processed as described. The nucleotides in red represent the mutation; wild type sequence is listed at the bottom. The mutation was identified in all samples.

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