Characteristics | Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|---|
 | No. (%) | pvalue | Hazard ratio | 95% CI | Pvalue |
Sex | Â | 0.766 | Â | Â | Â |
Male | 341 (80.6) | Â | Â | Â | Â |
Female | 82 (19.4) | Â | Â | Â | Â |
Age (yr) | Â | 0.013* | 1.473 | 1.079 - 2.012 | 0.015* |
≤54 | 146 (34.5) |  |  |  |  |
>54 | 277 (65.5) | Â | Â | Â | Â |
Tumor location | Â | 0.485 | Â | Â | Â |
Upper | 36 (8.5) | Â | Â | Â | Â |
Middle | 252 (59.6) | Â | Â | Â | Â |
Lower | 135 (31.9) | Â | Â | Â | Â |
Degree of differentiation | Â | 0.167 | Â | Â | Â |
Poorly or not differentiated | 159 (37.6) | Â | Â | Â | Â |
Moderately differentiated | 251 (59.3) | Â | Â | Â | Â |
Poorly differentiated | 13 (3.1) | Â | Â | Â | Â |
TNM stage (AJCC, 7th) | Â | <0.001* | Â | Â | <0.001* |
I | 54 (12.8) | Â | 1 | Reference | Â |
II | 168 (39.7) |  | 1.913 | 0.973 – 3.760 | 0.060 |
III | 142 (33.6) |  | 4.231 | 2.178 – 8.220 | <0.001* |
IV | 59 (13.9) |  | 3.552 | 1.405 – 8.978 | 0.007* |
Distant metastasis | Â | <0.001* | Â | Â | Â |
No | 364 (86.1) | Â | Â | Â | Â |
Yes | 59 (13.9) | Â | Â | Â | Â |
Surgery | Â | <0.001* | Â | Â | Â |
No | 60 (14.2) | Â | Â | Â | Â |
Yes | 363 (85.8) | Â | Â | Â | Â |
Treatment purpose |  | <0.001* | 2.113 | 1.099 – 4.061 | 0.025* |
Curative treatment | 358 (84.6) | Â | Â | Â | Â |
Palliative treatment | 65 (15.2) | Â | Â | Â | Â |
BMI (Kg/m2) |  | <0.001* | 0.663 | 0.496 – 0.885 | 0.005* |
≤20.43 | 158 (37.4) |  |  |  |  |
>20.43 | 257 (60.8) | Â | Â | Â | Â |
CRP/Alb |  | <0.001* | 1.393 | 1.031 – 1.883 | 0.031* |
≤0.095 | 276 (65.2) |  |  |  |  |
>0.095 | 147 (34.8) | Â | Â | Â | Â |
mGPS | Â | 0.003* | Â | Â | Â |
0 | 345 (81.6) | Â | Â | Â | Â |
1 | 70 (16.5) | Â | Â | Â | Â |
2 | 8 (1.9) | Â | Â | Â | Â |
PNI | Â | 0.002* | Â | Â | Â |
≤49.05 | 102 (24.1) |  |  |  |  |
>49.05 | 321 (75.9) | Â | Â | Â | Â |
NLR | Â | 0.018* | Â | Â | Â |
≤1.835 | 139 (32.9) |  |  |  |  |
>1.835 | 284 (67.1) | Â | Â | Â | Â |
PLR | Â | 0.026* | Â | Â | Â |
≤163.8 | 327 (77.3) |  |  |  |  |
>163.8 | 96 (22.7) | Â | Â | Â | Â |
CRP (mg/L) | Â | 0.002* | Â | Â | Â |
≤10 | 345 (81.6) |  |  |  |  |
>10 | 78 (18.4) | Â | Â | Â | Â |
WBC (×10^9/L) |  | 0.365 |  |  |  |
≤10 | 373 (88.2) |  |  |  |  |
>10 | 50 (11.8) | Â | Â | Â | Â |
Albumin (g/L) | Â | 0.041* | Â | Â | Â |
≤35 | 8 (1.9) |  |  |  |  |
>35 | 415 (98.1) | Â | Â | Â | Â |