Patient | Age (years) | Gender | FAB | Leukocyte (/μL) | Cytogenetics | Initial CNS disease | CNS Symptoms | Radiation therapy* | HSCT | Time from remission to CNS relapse (months) | Time from CNS relapse to BM relapse (months) | Outcome after isolated CNS relapse |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 24 | M | M5 | 113510 | t(9;11;13)(p22;q23;q34) | Nil | Headache | No | Yes | 2 | - | CR in 41.6Â m |
2 | 28 | M | M4 | 172700 | t(11;19)(q23;p13) | Nil | Tremor | Yes | No | 14 | 5.8 | Died in 7.4Â m |
3 | 28 | F | M4 | 123550 | t(6;11)(q27;q23) | Nil | Dizziness | No | Yes | 3.3 | 14.9# | Died in 41.4Â m |
4 | 35 | M | M4 | 33510 | CN | Nil | Blurred vision | Yes | Yes | 3.2 | 2.3 | Died in 5.8Â m |