|
Variable
|
Univariate analysis
|
Multivariate analysis
|
|---|
| |
OR
|
95% CI
|
P
value
|
OR
|
95% CI
|
P
value
|
|
Age*
|
5.654
|
2.01-15.904
|
0.001
|
5.933
|
1.82-19.343
|
0.003
|
|
Sex
|
0.786
|
0.319-1.932
|
0.599
|
-
|
-
|
-
|
|
WBC†
|
4.069
|
1.616-10.244
|
0.003
|
3.136
|
1.083-9.078
|
0.035
|
|
Platelet§
|
2.303
|
0.755-7.026
|
0.143
|
2.804
|
0.799-9.837
|
0.107
|
|
LDH‡
|
1.931
|
0.688-5.425
|
0.212
|
-
|
-
|
-
|
|
FAB M4¶
|
3.143
|
1.266-7.803
|
0.014
|
2.023
|
0.646-6.341
|
0.227
|
|
inv(16) ∆
|
2.899
|
0.609-13.79
|
0.181
|
1.176
|
0.277-10.612
|
0.562
|
|
11q23 abnormalities#
|
9.307
|
2.615-33.123
|
0.001
|
5.548
|
1.208-25.489
|
0.028
|
- Only variables with P value < 0.2 in the univariate analysis were incorporated into the multivariate logistic regression analysis.
- *Age ≤ 45 y relative to age > 45 y.
- †WBC greater than or equal to 50,000/μL vs less than 50,000/μL.
- §Platelet greater than or equal to 30,000/μL vs less than 30,000/μL.
- ‡LDH greater than or equal to two times the upper limit of normal vs less than two times the upper limit of normal.
- ¶French-American-British M4 morphology vs others.
- ∆Inversion of chromosome 16 vs others.
- #chromosome translocations involving 11q23 vs others.
- Abbreviation: CNS, central nervous system; OR, odds ratio; CI, confidence interval; WBC, white blood cell; LDH, lactate dehydrogenase.
