Variables
|
Total (n = 395)
|
Patients with CNS involvement (n = 20)
|
Patients without CNS involvement (n = 375)
|
Pvalue
|
---|
Sex†
| | | |
0.648
|
Male
|
220
|
10(50)
|
210(56)
| |
Female
|
175
|
10(50)
|
165(44)
| |
Age (year)‡
|
53(18-90)
|
37.5(21-72)
|
54(18-90)
|
<0.001
|
Laboratory data‡
| | | | |
WBC (/μL)
|
21950(120-423000)
|
83865(1860-277250)
|
21050(120-423000)
|
0.003
|
Haemoglobin (g/dL)
|
8.1(2.9-14.5)
|
8.1(4.9-14.5)
|
8.1(2.9-14)
|
0.392
|
Platelet (×1,000 /μL)
|
45(1-802)
|
71.5(11-255)
|
44(1-802)
|
0.03
|
PBC (/μL)
|
9014(0-369070)
|
42751(0-260615)
|
8360(0-369070)
|
0.009
|
LDH (U/L)
|
859(206-13130)
|
1641.5(265-8693)
|
842(206-13130)
|
0.069
|
FAB†
| | | | |
M0
|
11
|
0(0)
|
11(2.9)
|
>0.999
|
M1
|
85
|
4(20)
|
81(21.6)
|
>0.999
|
M2
|
139
|
3(15)
|
136(36.3)
|
0.057
|
M4
|
116
|
11(55)
|
105(28)
|
0.02
|
M5
|
20
|
1(5)
|
19(5.1)
|
>0.999
|
M6
|
15
|
0(0)
|
15(4)
|
>0.999
|
Undetermined
|
9
|
1(5)
|
8(2.1)
|
0.377
|
- †number of patients (%).
- ‡median (range).
- Abbreviation: CNS central nervous system, WBC white blood cell, PBC peripheral blast cell, LDH lactate dehydrogenase, FAB French-American-British.