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Table 1 Correlation between lymphovascular invasion and clinicopathologic characteristics in gastric carcinoma

From: The prognostic significance of lymphovascular invasion in patients with resectable gastric cancer: a large retrospective study from Southern China

Variables

Lymphovascular invasion

All cases

Absence

Presence

P value*

Sex

   

0.955

  Female

354

229 (64.7%)

125 (35.3%)

 

  Male

794

515 (64.9%)

279 (35.1%)

 

Age at diagnosis (years)

   

0.458

  <60

574

378 (65.9%)

196 (34.1%)

 

  ≥60

574

366 (63.8%)

208 (36.2%)

 

CEA†

   

0.665

  Normal

791

525 (66.4%)

266 (33.6%)

 

  Elevated

157

107(68.2%)

50 (31.8%)

 

CA19-9‡

   

0.004

  Normal

707

487 (68.9%)

220 (31.1%)

 

  Elevated

195

113 (57.9%)

82 (42.1%)

 

Size (diameter), cm

   

<0.0001

  ≤5

697

487 (69.9%)

210 (30.1%)

 

  >5

451

257 (57.0%)

194 (43.0%)

 

Lauren classification

   

0.004

  Diffuse

585

356 (60.9%)

229 (39.1%)

 

  Mixed/ Intestinal

563

388 (68.9%)

175 (31.1%)

 

Differentiation

   

<0.0001

  Well/moderate

435

331 (76.1%)

104 (23.9%)

 

  Poor/undifferentiated

713

413 (57.9%)

300 (42.1%)

 

Gastric wall invasion

   

<0. 0001

  T1/T2

150

140 (93.3%)

10 (6.7%)

 

  T3/T4

998

604 (60.5%)

394 (39.5%)

 

Nodal metastasis

   

<0.0001

  N0

377

322 (85.4%)

55 (14.6%)

 

  N1-N3

771

422 (54.7%)

349 (45.3%)

 

Distant metastasis

   

<0.0001

  M0

1003

679 (67.7%)

324 (32.4%)

 

  M1

145

65 (44.8%)

80 (55.2%)

 

TNM stage

   

<0.0001

  I/II

486

409 (84.2%)

77 (15.8%)

 

  III/ IV

662

335 (50.6%)

327 (49.4%)

 
  1. *Chi-square test; †Preoperative serum CEA was measured in 948 patients; ‡Preoperative serum CA19-9 was measured in 902 patients; CEA indicates carcinoembryonic antigen; CA19-9 indicates carbohydrate antigen 19-9.