Table 4 Predictive factors for overall survival of UTUC patients after RNU

Age (y)

≥70 vs <70

1.036 (0.981-1.095)

0.207

Sex

Male vs female

4.195 (1.631-10.789)

0.003

4.155 (1.771-9.747)

0.001

BMI (kg/m2)

≥25 vs <25

0.933 (0.373-2.334)

0.882

Tumor side

Left vs Right

0.482 (0.172-1.356)

0.167

Tumor location

Ureter vs Pelvis

2.026 (0.524-7.836)

0.306

Tumor multiplicity

Multiple vs Single

1.041 (0.398-2.724)

0.935

Tumor size (cm)

≥3.5 vs <3.5

4.245 (1.526-11.803)

0.006

3.680 (1.495-9.056)

0.005

Tumor configuration

Nonpapillary vs Papillary

1.860 (0.676-5.116)

0.229

T stage

T2-T4 vs Ta-T1

4.172 (1.601-10.535)

0.004

4.035 (1.678-9.521)

0.001

G grade

High vs Low

0.932 (0.360-2.411)

0.885

eGFR (ml/min/1.73 m2)

<60 vs ≥60

1.247 (0.439-3.538)

0.678

Hydronephrosis

Present vs Absent

1.081 (0.294-3.981)

0.907

Lymph node stage

N+ vs N0

3.206 (0.715-14.378)

0.128

KPNA2 expression

High vs Low

3.443 (1.271-9.329)

0.015

4.480 (1.844-10.887)

0.001