Figure 5
From: Transient elevation of glycolysis confers radio-resistance by facilitating DNA repair in cells
DNP induced glycolysis facilitates repair of radiation-induced DNA double strand breaks. Effects of DNP (1 μM) induced glycolysis on the induction (A) and kinetics of repair (B) of radiation (5 Gy) induced DNA damage assayed using single-cell gel electrophoresis in BMG-1 cells. (C) Reduction in the radiation induced cytogenetic damage (micronuclei expression) observed in glycolysis stimulated (DNP treated) BMG-1, OCT-1 and HEK293 cells. The data shown are the mean values (±1 SD) of three independent experiments. Differences were statistically significant (*p < 0.05).