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Table 2 Univariate and Multivariate analyses of various prognostic parameters in patients with MIBC: Cox-regression analysis

From: Utility of SAM68 in the progression and prognosis for bladder cancer

  Univariate analysis Multivariate analysis
HR 95% CI p Value HR 95% CI p Value
pT stage (T3 ~ 4 vs. T2) 4.445 2.221 ~ 8.896 <0.001 2.308 1.047 ~ 5.089 0.038
pN stage (N+ vs. N) 4.944 2.313 ~ 10.780 <0.001 2.879 1.222 ~ 6.872 0.016
SAM68 level (High vs. low) 3.366 1.574 ~ 7.201 0.002 2.365 1.055 ~ 5.298 0.037
SAM68 Localization* 2.003 1.267 ~ 3.166 0.003 1.749 1.106 ~ 2.767 0.017
  1. MIBC: muscle invasive bladder cancer; HR: hazard ratio; CI, confidence interval.
  2. *nucleus-cytoplasm co-expression vs. expression in nucleus vs. expression in cytoplasm.