Figure 2

Expression of SAM68 protein was increased when bladder tumor developed from non-muscle invasive to muscle invasive. (A) Increased fold of SAM68 mRNA for muscle invasive tumor comparing to non-muscle invasive tumor from the same patient. (B) Immunohistochemistry study confirmed the expression of SAM68, in the protein level, was much higher in muscle invasive tumor samples than non-muscle invasive tumor from the same patient. For each pair of sample, the left panel represents non-muscle invasive bladder cancer (NMIBC) sample obtained from transurethral resection of bladder tumor and the right panel represents muscle invasive bladder cancer (MIBC) sample gained from radical cystectomy.