Skip to main content

Table 4 Multivariate cox regression analysis of clinical characteristics and JWA, XRCC1 and BRCA1 expression associated with survival

From: Effects of JWA, XRCC1 and BRCA1 mRNA expression on molecular staging for personalized therapy in patients with advanced esophageal squamous cell carcinoma

Clinical variables HR 95%CI P value
Gender (females vs. males) 0.83 0.56-1.22 0.349
ECOG, PS (0-1 vs. 2) 0.70 0.59-1.43 0.701
TNM stage (II vs. III or III vs. IV) 0.57 0.74-1.18 0.567
G stage (G1 vs. G2 or G2 vs. G3) 1.45 1.06-1.97 0.019
JWA (low vs. high) 0.22 0.13-0.37 <0.001
XRCC1 (low vs. high) 0.36 0.21-0.63 <0.001
BRCA1 (low vs. high) 1.14 0.80-1.62 0.485
  1. HR = hazard ratios; y = years; G = differentiation grade; RR = response rate; CI = confidence interval.