Skip to main content

Table 4 Multivariate cox regression analysis of clinical characteristics and JWA, XRCC1 and BRCA1 expression associated with survival

From: Effects of JWA, XRCC1 and BRCA1 mRNA expression on molecular staging for personalized therapy in patients with advanced esophageal squamous cell carcinoma

Clinical variables

HR

95%CI

P value

Gender (females vs. males)

0.83

0.56-1.22

0.349

ECOG, PS (0-1 vs. 2)

0.70

0.59-1.43

0.701

TNM stage (II vs. III or III vs. IV)

0.57

0.74-1.18

0.567

G stage (G1 vs. G2 or G2 vs. G3)

1.45

1.06-1.97

0.019

JWA (low vs. high)

0.22

0.13-0.37

<0.001

XRCC1 (low vs. high)

0.36

0.21-0.63

<0.001

BRCA1 (low vs. high)

1.14

0.80-1.62

0.485

  1. HR = hazard ratios; y = years; G = differentiation grade; RR = response rate; CI = confidence interval.