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Table 3 Treatment outcomes according to genes expression levels

From: Effects of JWA, XRCC1 and BRCA1 mRNA expression on molecular staging for personalized therapy in patients with advanced esophageal squamous cell carcinoma

  RR, N (%) mOS (months)
Gene Level No. CR + PR SD + PD P value Median (95% CI) P value
JWA Low 73 68.5 31.5   8.0(6.6-9.4)  
  High 72 83.3 16.7 0.052 19.0(15.8-22.2) <0.001
XRCC1 Low 73 68.5 31.5   9.0(7.5-10.5)  
  High 72 83.3 16.7 0.052 19.0(15.4-22.6) <0.001
BRCA1 Low 74 79.7 20.3   15.0(14.4-17.6)  
  High 71 71.8 28.2 0.267 14.0(11.5-14.5) 0.429
  1. mOS = median overall survival; RR = response rate; CI = confidence interval; CR = complete response; PR = partial response; SD = stable disease; PD = progress disease.