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Table 2 Univariate and multivariate cox regression analyses of prognostic factors in nasopharyngeal carcinoma

From: High expression of Talin-1 is associated with poor prognosis in patients with nasopharyngeal carcinoma

 

Univariate analysis

Multivariate analysis

Variable

HR

95% CI

P-value*

HR

95% CI

P-value*

Overall survival

Talin-1 expression (high vs. low)

2.15

1.28-3.63

0.004

1.87

1.10-3.16

0.02

TNM stage (III-IV vs. I-II)

3.06

1.45-6.47

0.003

2.97

1.40-6.29

0.005

Age (≥45 years vs. <45 years)

1.63

0.96-2.78

0.07

   

Sex (male vs. female)

1.57

0.83-2.96

0.17

   

WHO Type (III vs. I-II)

0.63

0.20-2.03

0.44

   

VCA-IgA (≥1:80 vs. < 1:80)

1.50

0.64-3.49

0.35

   

EA-IgA (≥1:10 vs. < 1:10)

1.04

0.56-1.93

0.90

   

Distant metastasis-free survival

Talin-1 expression (high vs. low)

2.39

1.38-4.15

0.002

2.18

1.25-3.78

0.006

TNM stage (III-IV vs. I-II)

3.78

1.61-8.86

0.002

3.48

1.48-8.17

0.004

Age (≥45 years vs. < 45 years)

1.58

0.90-2.78

0.11

   

Sex (male vs. female)

1.51

0.77-2.94

0.23

   

WHO Type (III vs. I-II)

0.54

0.17-1.73

0.30

   

VCA-IgA (≥1:80 vs. < 1:80)

1.10

0.50-2.45

0.81

   

EA-IgA (≥1:10 vs. < 1:10)

1.30

0.65-2.60

0.45

   
  1. Abbreviations: WHO: World Health Organization; VCA-IgA: viral capsid antigen immunoglobulin A; EA-IgA: early antigen immunoglobulin A. P-values* were calculated using univariate and multivariate cox regression analyses.