Table 3 Summary of all-causality adverse events occurring in >2 patients in the ITT population during the study period*
Adverse event | Cisplatin + gemcitabine + axitinib (n = 38) | |||
|---|---|---|---|---|
All grades | Grade ≥3 | |||
No. | % | No. | % | |
Nausea | 16 | 42.1 | ||
Anaemia | 12 | 31.6 | 3 | 7.9 |
Vomiting | 11 | 28.9 | 2 | 5.3 |
Hypertension | 10 | 26.3 | 5 | 13.2 |
Neutropaenia | 9 | 23.7 | 5 | 13.2 |
Weight loss | 9 | 23.7 | 0 | 0 |
Appetite loss | 8 | 21.1 | 0 | 0 |
Fatigue | 7 | 18.4 | 3 | 7.9 |
Asthenia | 6 | 15.8 | 0 | 0 |
Leukopaenia | 5 | 13.2 | 2 | 5.3 |
Diarrhoea | 5 | 13.2 | 0 | 0 |
Reduced creatinine clearance | 5 | 13.2 | 0 | 0 |
Alopecia | 5 | 13.2 | 0 | 0 |
Thrombocytopaenia | 4 | 10.5 | 0 | 0 |
Chest pain | 4 | 10.5 | 0 | 0 |
Toxic nephropathy | 4 | 10.5 | 0 | 0 |
Cough | 4 | 10.5 | 0 | 0 |
Dyspnoea | 4 | 10.5 | 0 | 0 |
Rash | 4 | 10.5 | 0 | 0 |
Pulmonary cavitation | 3 | 7.9 | 1 | 2.6 |
Haemoptysis | 3 | 7.9 | 1 | 2.6 |