Figure 1

Mitochondrial ND6 gene nonsense and missense mutations in lung adenocarcinoma patients. (A-K) DNA sequencing electropherograms showing point mutations of mitochondrial ND6 gene lead to the amino acid changes of the protein in 11 cases. (A-H) represent missense mutation and (I-J) represent nonsense mutation. (L) The average age of the patients with or without mitND6 gene mutation. Each dot represents the age of a patient (n = 24 for patients with mitND6 gene mutation, n = 63 for patients without mitND6 gene mutation) with the line indicating the mean level; *, P < 0.05. (M) The survival rate of the patients with or without mitND6 gene mutation. n = 11 for patients with missense and nonsense mitND6 gene mutation, n = 13 for patients with samesense mitND6 gene mutation, n = 63 for patients without mitND6 gene mutation.