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Table 1 Recovery of 5-FU in rat plasma and lymphatic fluid

From: Local pelvic irradiation modulates Pharmacokinetics of 5-Fluorouracil in the plasma but not in the Lymphatic System

Matrices Nominal concentration (μg/mL) Set 1 Peak area Set 2 Peak area Recovery (%)
Plasma 1 66301 ± 412 39467 ± 1211 59.53 ± 1.83
  10 632542 ± 4183 355741 ± 14191 56.24 ± 2.24
  100 6463129 ± 22755 3631833 ± 429923 56.19 ± 6.65
  Mean ± SD    57.32 ± 4.25
Lymphatic fluid 1 66301 ± 412 38174 ± 1136 57.58 ± 1.71
  10 632542 ± 4183 336695 ± 32677 53.23 ± 5.17
  100 6463129 ± 22755 3689380 ± 141268 57.08 ± 2.19
  Mean ± SD    55.96 ± 3.76
  1. Data expressed as mean ± SD (n = 6). Recovery calculated as the ratio of the mean peak area of an analyte spiked before extraction (set 2) to the mean peak area of an analyte spiked in the neat mobile phase (set 1) multiplied by 100.