Table 2 Association between nuclear fraction of Bcl3 and clinicopathological parameters
From: Early diagnostic value of Bcl-3 localization in colorectal cancer
Bcl3 nuclear fraction | ||||||
|---|---|---|---|---|---|---|
Variable | 0-25% | 26-50% | 51-75% | 76-100% | r | P † |
N (%) | 108 (41) | 48 (18) | 20 (8) | 88 (33) | ||
Age | ||||||
≤75 | 59 (55) | 30 (63) | 10 (50) | 48 (55) | 0.004 | 0.948 |
>75 | 49 (45) | 18 (37) | 10 (50) | 40 (45) | ||
Gender | ||||||
Female | 55 (51) | 25 (52) | 9 (45) | 44 (50) | 0.012 | 0.848 |
Male | 53 (49) | 23 (48) | 11 (55) | 44 (50) | ||
Tumour stage | ||||||
T1 | 8 (8) | 2 (4) | 0 (0) | 10 (11,5) | −0.097 | 0.118 |
T2 | 22 (20) | 15 (33) | 4 (21) | 26 (30) | ||
T3 | 63 (59) | 26 (57) | 12 (63) | 41 (47) | ||
T4 | 14 (13) | 3 (6) | 3 (16) | 10 (11,5) | ||
Node stage | ||||||
N0 | 60 (56) | 34 (74) | 10 (53) | 64 (75) | −0.159 | 0.011 |
N1 | 29 (27) | 10 (22) | 7 (37) | 14 (16) | ||
N2 | 18 (17) | 2 (4) | 2 (10) | 8 (9) | ||
Differentiation grade | ||||||
High | 9 (8) | 2 (4) | 0 (0) | 10 (11) | −0.045 | 0.468 |
Intermediate | 67 (62) | 37 (77) | 15 (75) | 55 (63) | ||
Low | 32 (30) | 9 (19) | 5 (25) | 23 (26) | ||
Ki67 nuclear fraction | ||||||
0-25% | 8 (8) | 6 (13) | 0 (0) | 3 (4) | 0.186 | 0.003 |
26-50% | 15 (14) | 4 (8) | 1 (5) | 4 (5) | ||
51-75% | 35 (33) | 13 (27) | 4 (20) | 24 (28) | ||
76-100% | 48 (45) | 25 (52) | 15 (75) | 53 (63) | ||
Bcl3 nuclear intensity | ||||||
0 (absent) | 44 (41) | 0 (0) | 0 (0) | 0 (0) | 0.512 | <0.001 |
1 | 6 (5) | 6 (13) | 1 (5) | 4 (5) | ||
2 | 33 (31) | 16 (33) | 2 (10) | 19 (22) | ||
3 | 19 (18) | 22 (46) | 12 (60) | 48 (54) | ||
4 | 6 (5) | 4 (8) | 5 (25) | 17 (19) | ||
Bcl3 cytoplasmic intensity | ||||||
0 (absent) | 5 (5) | 1 (1) | 0 (0) | 1 (1) | 0.190 | 0.002 |
1 | 55 (51) | 20 (42) | 8 (40) | 30 (34) | ||
2 | 38 (35) | 19 (40) | 7 (35) | 42 (48) | ||
3 | 10 (9) | 8 (17) | 5 (25) | 15 (17) | ||