TY - JOUR AU - Benson, J. R. AU - Jatoi, I. AU - Keisch, M. AU - Esteva, F. J. AU - Makris, A. AU - Jordan, V. C. PY - 2009 DA - 2009// TI - Early breast cancer JO - Lancet VL - 373 UR - https://doi.org/10.1016/S0140-6736(09)60316-0 DO - 10.1016/S0140-6736(09)60316-0 ID - Benson2009 ER - TY - JOUR AU - Jones, P. A. AU - Baylin, S. B. PY - 2007 DA - 2007// TI - The epigenomics of cancer JO - Cell VL - 128 UR - https://doi.org/10.1016/j.cell.2007.01.029 DO - 10.1016/j.cell.2007.01.029 ID - Jones2007 ER - TY - JOUR AU - Baylin, S. B. AU - Esteller, M. AU - Rountree, M. R. AU - Bachman, K. E. AU - Schuebel, K. AU - Herman, J. G. PY - 2001 DA - 2001// TI - Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer JO - Hum Mol Genet VL - 10 UR - https://doi.org/10.1093/hmg/10.7.687 DO - 10.1093/hmg/10.7.687 ID - Baylin2001 ER - TY - JOUR AU - Baylin, S. AU - Herman, J. AU - Graff, J. AU - Vertino, P. AU - Issa, J. PY - 1998 DA - 1998// TI - Alterations in DNA methylation: a fundamental aspect of neoplasia JO - Adv Cancer Res. VL - 72 UR - https://doi.org/10.1016/S0065-230X(08)60702-2 DO - 10.1016/S0065-230X(08)60702-2 ID - Baylin1998 ER - TY - JOUR AU - Nathan, D. AU - Crothers, D. M. PY - 2002 DA - 2002// TI - Bending and flexibility of methylated and unmethylated EcoRI DNA JO - J Mol Biol VL - 316 UR - https://doi.org/10.1006/jmbi.2001.5247 DO - 10.1006/jmbi.2001.5247 ID - Nathan2002 ER - TY - JOUR AU - Cedar, H. AU - Bergman, Y. PY - 2009 DA - 2009// TI - Linking DNA methylation and histone modification: patterns and paradigms JO - Nat Rev Genet VL - 10 UR - https://doi.org/10.1038/nrg2540 DO - 10.1038/nrg2540 ID - Cedar2009 ER - TY - JOUR AU - Ehrlich, M. AU - Lacey, M. PY - 2013 DA - 2013// TI - DNA methylation and differentiation: silencing, upregulation and modulation of gene expression JO - Epigenomics VL - 5 UR - https://doi.org/10.2217/epi.13.43 DO - 10.2217/epi.13.43 ID - Ehrlich2013 ER - TY - JOUR AU - Blattler, A. AU - Yao, L. AU - Witt, H. AU - Guo, Y. AU - Nicolet, C. M. AU - Berman, B. P. PY - 2014 DA - 2014// TI - Global loss of DNA methylation uncovers intronic enhancers in genes showing expression changes JO - Genome Biol VL - 15 UR - https://doi.org/10.1186/s13059-014-0469-0 DO - 10.1186/s13059-014-0469-0 ID - Blattler2014 ER - TY - JOUR AU - Maunakea, A. K. AU - Nagarajan, R. P. AU - Bilenky, M. AU - Ballinger, T. J. AU - D'Souza, C. AU - Fouse, S. D. PY - 2010 DA - 2010// TI - Conserved role of intragenic DNA methylation in regulating alternative promoters JO - Nature VL - 466 UR - https://doi.org/10.1038/nature09165 DO - 10.1038/nature09165 ID - Maunakea2010 ER - TY - JOUR AU - Malousi, A. AU - Kouidou, S. PY - 2012 DA - 2012// TI - DNA hypermethylation of alternatively spliced and repeat sequences in humans JO - Mol Genet Genomics VL - 287 UR - https://doi.org/10.1007/s00438-012-0703-y DO - 10.1007/s00438-012-0703-y ID - Malousi2012 ER - TY - JOUR AU - Brenet, F. AU - Moh, M. AU - Funk, P. AU - Feierstein, E. AU - Viale, A. J. AU - Socci, N. D. PY - 2011 DA - 2011// TI - DNA methylation of the first exon is tightly linked to transcriptional silencing JO - PLoS One VL - 6 UR - https://doi.org/10.1371/journal.pone.0014524 DO - 10.1371/journal.pone.0014524 ID - Brenet2011 ER - TY - JOUR AU - Cleator, S. J. AU - Ahamed, E. AU - Coombes, R. C. AU - Palmieri, C. PY - 2009 DA - 2009// TI - A 2009 update on the treatment of patients with hormone receptor-positive breast cancer JO - Clin Breast Cancer. VL - 9 UR - https://doi.org/10.3816/CBC.2009.s.001 DO - 10.3816/CBC.2009.s.001 ID - Cleator2009 ER - TY - JOUR AU - Sorlie, T. AU - Wang, Y. AU - Xiao, C. AU - Johnsen, H. AU - Naume, B. AU - Samaha, R. R. PY - 2006 DA - 2006// TI - Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms JO - BMC Genomics. VL - 7 UR - https://doi.org/10.1186/1471-2164-7-127 DO - 10.1186/1471-2164-7-127 ID - Sorlie2006 ER - TY - JOUR AU - Carey, L. A. PY - 2010 DA - 2010// TI - Through a glass darkly: advances in understanding breast cancer biology, 2000–2010 JO - Clin Breast Cancer VL - 10 UR - https://doi.org/10.3816/CBC.2010.n.026 DO - 10.3816/CBC.2010.n.026 ID - Carey2010 ER - TY - JOUR AU - Flanagan, J. M. AU - Munoz-Alegre, M. AU - Henderson, S. AU - Tang, T. AU - Sun, P. AU - Johnson, N. PY - 2009 DA - 2009// TI - Gene-body hypermethylation of ATM in peripheral blood DNA of bilateral breast cancer patients JO - Human Molecular Genetics VL - 18 UR - https://doi.org/10.1093/hmg/ddp033 DO - 10.1093/hmg/ddp033 ID - Flanagan2009 ER - TY - JOUR AU - Zemach, A. AU - Zilberman, D. PY - 2010 DA - 2010// TI - Evolution of eukaryotic DNA methylation and the pursuit of safer sex JO - Curr Biol VL - 20 UR - https://doi.org/10.1016/j.cub.2010.07.007 DO - 10.1016/j.cub.2010.07.007 ID - Zemach2010 ER - TY - JOUR AU - Zilberman, D. AU - Gehring, M. AU - Tran, R. K. AU - Ballinger, T. AU - Henikoff, S. PY - 2007 DA - 2007// TI - Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription JO - Nature Genetics VL - 39 UR - https://doi.org/10.1038/ng1929 DO - 10.1038/ng1929 ID - Zilberman2007 ER - TY - JOUR AU - Zemach, A. AU - McDaniel, I. E. AU - Silva, P. AU - Zilberman, D. PY - 2010 DA - 2010// TI - Genome-wide evolutionary analysis of eukaryotic DNA methylation JO - Science VL - 328 UR - https://doi.org/10.1126/science.1186366 DO - 10.1126/science.1186366 ID - Zemach2010 ER - TY - JOUR AU - Aran, D. AU - Toperoff, G. AU - Rosenberg, M. AU - Hellman, A. PY - 2011 DA - 2011// TI - Replication timing-related and gene body-specific methylation of active human genes JO - Hum Mol Genet VL - 20 UR - https://doi.org/10.1093/hmg/ddq513 DO - 10.1093/hmg/ddq513 ID - Aran2011 ER - TY - JOUR AU - Tost, J. PY - 2010 DA - 2010// TI - DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker JO - Molecular Biotechnology VL - 44 UR - https://doi.org/10.1007/s12033-009-9216-2 DO - 10.1007/s12033-009-9216-2 ID - Tost2010 ER - TY - JOUR AU - Royo, J. L. AU - Hidalgo, M. AU - Ruiz, A. PY - 2007 DA - 2007// TI - Pyrosequencing protocol using a universal biotinylated primer for mutation detection and SNP genotyping JO - Nature Protocols VL - 2 UR - https://doi.org/10.1038/nprot.2007.244 DO - 10.1038/nprot.2007.244 ID - Royo2007 ER - TY - JOUR AU - Madureira, P. A. AU - Varshochi, R. AU - Constantinidou, D. AU - Francis, R. E. AU - Coombes, R. C. AU - Yao, K. M. PY - 2006 DA - 2006// TI - The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer cells JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M603906200 DO - 10.1074/jbc.M603906200 ID - Madureira2006 ER - TY - JOUR AU - Chan, T. A. AU - Glockner, S. AU - Yi, J. M. AU - Chen, W. AU - Neste, L. AU - Cope, L. PY - 2008 DA - 2008// TI - Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis JO - PLoS Med VL - 5 UR - https://doi.org/10.1371/journal.pmed.0050114 DO - 10.1371/journal.pmed.0050114 ID - Chan2008 ER - TY - JOUR AU - Miranda, T. B. AU - Cortez, C. C. AU - Yoo, C. B. AU - Liang, G. AU - Abe, M. AU - Kelly, T. K. PY - 2009 DA - 2009// TI - DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation JO - Mol Cancer Ther VL - 8 UR - https://doi.org/10.1158/1535-7163.MCT-09-0013 DO - 10.1158/1535-7163.MCT-09-0013 ID - Miranda2009 ER - TY - JOUR AU - Feinberg, A. AU - Vogelstein, B. PY - 1983 DA - 1983// TI - Hypomethylation distinguishes genes of some human cancers from their normal counterparts JO - Nature VL - 301 UR - https://doi.org/10.1038/301089a0 DO - 10.1038/301089a0 ID - Feinberg1983 ER - TY - JOUR AU - Yang, X. AU - Han, H. AU - Carvalho, D. D. AU - Lay, F. D. AU - Jones, P. A. AU - Liang, G. PY - 2014 DA - 2014// TI - Gene body methylation can alter gene expression and is a therapeutic target in cancer JO - Cancer Cell VL - 26 UR - https://doi.org/10.1016/j.ccr.2014.07.028 DO - 10.1016/j.ccr.2014.07.028 ID - Yang2014 ER - TY - JOUR AU - Kulis, M. AU - Queiros, A. C. AU - Beekman, R. AU - Martin-Subero, J. I. PY - 2013 DA - 2013// TI - Intragenic DNA methylation in transcriptional regulation, normal differentiation and cancer JO - Biochim Biophys Acta VL - 1829 UR - https://doi.org/10.1016/j.bbagrm.2013.08.001 DO - 10.1016/j.bbagrm.2013.08.001 ID - Kulis2013 ER - TY - JOUR AU - Zemach, A. AU - Kim, M. Y. AU - Silva, P. AU - Rodrigues, J. A. AU - Dotson, B. AU - Brooks, M. D. PY - 2010 DA - 2010// TI - Local DNA hypomethylation activates genes in rice endosperm JO - Proc Natl Acad Sci USA VL - 107 UR - https://doi.org/10.1073/pnas.1009695107 DO - 10.1073/pnas.1009695107 ID - Zemach2010 ER - TY - JOUR AU - Maunakea, A. K. AU - Chepelev, I. AU - Cui, K. AU - Zhao, K. PY - 2013 DA - 2013// TI - Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition JO - Cell Res VL - 23 UR - https://doi.org/10.1038/cr.2013.110 DO - 10.1038/cr.2013.110 ID - Maunakea2013 ER - TY - JOUR AU - Schor, I. E. AU - Fiszbein, A. AU - Petrillo, E. AU - Kornblihtt, A. R. PY - 2013 DA - 2013// TI - Intragenic epigenetic changes modulate NCAM alternative splicing in neuronal differentiation JO - Embo J VL - 32 UR - https://doi.org/10.1038/emboj.2013.167 DO - 10.1038/emboj.2013.167 ID - Schor2013 ER - TY - JOUR AU - Lorincz, M. AU - Dickerson, D. AU - Schmitt, M. AU - Groudine, M. PY - 2004 DA - 2004// TI - Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells JO - Nat Struct Mol Biol VL - 11 UR - https://doi.org/10.1038/nsmb840 DO - 10.1038/nsmb840 ID - Lorincz2004 ER - TY - STD TI - Pleyer L, Greil R. Digging deep into “dirty” drugs - modulation of the methylation machinery. Drug Metab Rev. 2015:1–28. ID - ref32 ER - TY - JOUR AU - Shenker, N. AU - Flanagan, J. M. PY - 2012 DA - 2012// TI - Intragenic DNA methylation: implications of this epigenetic mechanism for cancer research JO - Br J Cancer VL - 106 UR - https://doi.org/10.1038/bjc.2011.550 DO - 10.1038/bjc.2011.550 ID - Shenker2012 ER - TY - JOUR AU - Velicescu, M. AU - Weisenberger, D. J. AU - Gonzales, F. A. AU - Tsai, Y. C. AU - Nguyen, C. T. AU - Jones, P. A. PY - 2002 DA - 2002// TI - Cell division is required for de novo methylation of CpG islands in bladder cancer cells JO - Cancer Res VL - 62 ID - Velicescu2002 ER - TY - JOUR AU - Kangaspeska, S. AU - Stride, B. AU - Metivier, R. AU - Polycarpou-Schwarz, M. AU - Ibberson, D. AU - Carmouche, R. P. PY - 2008 DA - 2008// TI - Transient cyclical methylation of promoter DNA JO - Nature VL - 452 UR - https://doi.org/10.1038/nature06640 DO - 10.1038/nature06640 ID - Kangaspeska2008 ER - TY - JOUR AU - Metivier, R. AU - Gallais, R. AU - Tiffoche, C. AU - Peron, C. AU - Jurkowska, R. Z. AU - Carmouche, R. P. PY - 2008 DA - 2008// TI - Cyclical DNA methylation of a transcriptionally active promoter JO - Nature VL - 452 UR - https://doi.org/10.1038/nature06544 DO - 10.1038/nature06544 ID - Metivier2008 ER - TY - JOUR AU - Ooi, S. K. AU - Bestor, T. H. PY - 2008 DA - 2008// TI - The colorful history of active DNA demethylation JO - Cell VL - 133 UR - https://doi.org/10.1016/j.cell.2008.06.009 DO - 10.1016/j.cell.2008.06.009 ID - Ooi2008 ER - TY - JOUR AU - Jones, P. A. AU - Baylin, S. B. PY - 2002 DA - 2002// TI - The fundamental role of epigenetic events in cancer JO - Nature Reviews Genetics VL - 3 ID - Jones2002 ER - TY - JOUR AU - Feinberg, A. P. AU - Tycko, B. PY - 2004 DA - 2004// TI - The history of cancer epigenetics JO - Nature Reviews Cancer VL - 4 UR - https://doi.org/10.1038/nrc1279 DO - 10.1038/nrc1279 ID - Feinberg2004 ER - TY - JOUR AU - Kanai, Y. PY - 2010 DA - 2010// TI - Genome-wide DNA, methylation profiles in precancerous conditions and cancers JO - Cancer Sci VL - 101 UR - https://doi.org/10.1111/j.1349-7006.2009.01383.x DO - 10.1111/j.1349-7006.2009.01383.x ID - Kanai2010 ER - TY - JOUR AU - Veeck, J. AU - Esteller, M. PY - 2010 DA - 2010// TI - Breast cancer epigenetics: from DNA methylation to microRNAs JO - J Mammary Gland Biol Neoplasia VL - 15 UR - https://doi.org/10.1007/s10911-010-9165-1 DO - 10.1007/s10911-010-9165-1 ID - Veeck2010 ER - TY - JOUR AU - Mulero-Navarro, S. AU - Esteller, M. PY - 2008 DA - 2008// TI - Epigenetic biomarkers for human cancer: the time is now JO - Crit Rev Oncol Hematol VL - 68 UR - https://doi.org/10.1016/j.critrevonc.2008.03.001 DO - 10.1016/j.critrevonc.2008.03.001 ID - Mulero-Navarro2008 ER - TY - JOUR AU - Michels, K. B. PY - 2010 DA - 2010// TI - The promises and challenges of epigenetic epidemiology JO - Experimental gerontology VL - 45 UR - https://doi.org/10.1016/j.exger.2009.12.011 DO - 10.1016/j.exger.2009.12.011 ID - Michels2010 ER - TY - JOUR AU - Huang, Z. AU - Murphy, S. K. PY - 2013 DA - 2013// TI - Increased Intragenic IGF2 Methylation is Associated with Repression of Insulator Activity and Elevated Expression in Serous Ovarian Carcinoma JO - Front Oncol. VL - 3 ID - Huang2013 ER - TY - JOUR AU - Wild, L. AU - Flanagan, J. M. PY - 2010 DA - 2010// TI - Genome-wide hypomethylation in cancer may be a passive consequence of transformation JO - Biochim Biophys Acta VL - 1806 ID - Wild2010 ER - TY - JOUR AU - Heijmans, B. T. AU - Mill, J. PY - 2012 DA - 2012// TI - Commentary: The seven plagues of epigenetic epidemiology JO - Int J Epidemiol VL - 41 UR - https://doi.org/10.1093/ije/dyr225 DO - 10.1093/ije/dyr225 ID - Heijmans2012 ER - TY - JOUR AU - Hassiotou, F. AU - Geddes, D. T. AU - Hartmann, P. E. PY - 2013 DA - 2013// TI - Cells in human milk: state of the science JO - J Hum Lact VL - 29 UR - https://doi.org/10.1177/0890334413477242 DO - 10.1177/0890334413477242 ID - Hassiotou2013 ER - TY - JOUR AU - Faupel-Badger, J. M. AU - Arcaro, K. F. AU - Balkam, J. J. AU - Eliassen, A. H. AU - Hassiotou, F. AU - Lebrilla, C. B. PY - 2013 DA - 2013// TI - Postpartum remodeling, lactation, and breast cancer risk: summary of a National Cancer Institute-sponsored workshop JO - J Natl Cancer Inst VL - 105 UR - https://doi.org/10.1093/jnci/djs505 DO - 10.1093/jnci/djs505 ID - Faupel-Badger2013 ER - TY - JOUR AU - Gur-Dedeoglu, B. AU - Konu, O. AU - Bozkurt, B. AU - Ergul, G. AU - Seckin, S. AU - Yulug, I. G. PY - 2009 DA - 2009// TI - Identification of endogenous reference genes for qRT-PCR analysis in normal matched breast tumor tissues JO - Oncol Res VL - 17 UR - https://doi.org/10.3727/096504009788428460 DO - 10.3727/096504009788428460 ID - Gur-Dedeoglu2009 ER - TY - JOUR AU - Cong, L. AU - Ran, F. A. AU - Cox, D. AU - Lin, S. AU - Barretto, R. AU - Habib, N. PY - 2013 DA - 2013// TI - Multiplex genome engineering using CRISPR/Cas systems JO - Science VL - 339 UR - https://doi.org/10.1126/science.1231143 DO - 10.1126/science.1231143 ID - Cong2013 ER -