Table 1 Summary of dose level and dose-limiting toxicities in phase 1
Patient no. | Dose level | Dose-limiting toxicities |
|---|---|---|
001 | 1 | nil |
002 | 1 | nil |
003 | 1 | nil |
004 | 2 | nil |
005 | 2 | nil |
006 | 2 | nil |
007 | 3 | nil |
008 | 3 | Grade 3 syncope |
009 | 3 | nil |
010 | 3 | nil |
011 | 3 | nil |
012 | 3 | Treatment delay for > 2 weeks due to prolonged neutropenia |
013 | 2 | nil |
014 | 2 | nil |
015 | 2 | nil |
016 | 2 | nil |
017 | 2 | nil |
018 | 2 | nil |
019 | 2 | nil |