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Table 1 Absolute values of the whole tumor and the hypervascular area at baseline and follow-up for the therapy and control group (parameters: relative Blood Volume, mean Transit Time (s), Perfusion Index (rBV/mTT), Wash-in Rate)

From: Reducing tumor growth and angiogenesis using a triple therapy measured with Contrast-enhanced ultrasound (CEUS)

 

Whole tumor

 

Hypervascular area

 
 

Baseline

 

Follow-up

 

P

Baseline

 

Follow-up

 

p

 

Mean

SD

Mean

SD

 

Mean

SD

Mean

SD

 

Therapy: relative Blood Volume

337.3

273

164.3

193.7

0.01

595.4

448.8

190.3

57.4

0.01

Control: relative Blood Volume

131.6

72

529.9

237.2

0.01

320.8

183.5

414.9

51.1

0.16

Therapy: mean Transit Time (s)

4.2

2.0

8.3

5.1

0.01

4.8

2.3

13.2

6.5

0.01

Control: mean Transit Time (s)

6.8

5.2

4.5

1.9

0.18

4.7

2.6

6.6

5.6

0.34

Therapy: Perfusion Index (rBV/mTT)

102.6

96

27.4

39.3

0.01

177.2

197.0

32.0

50.9

0.01

Control: Perfusion Index (rBV/mTT)

30.2

25

123.9

63.7

0.01

91.2

57.4

121.8

95.2

0.38

Therapy: Wash-in Rate

37.5

33

11.7

8.3

0.01

102.8

76.8

25.5

14.3

0.01

Control: Wash-in Rate

21.6

16

27.9

25.8

0.6

63.6

39.8

154.3

84.4

0.01