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Table 1 Absolute values of the whole tumor and the hypervascular area at baseline and follow-up for the therapy and control group (parameters: relative Blood Volume, mean Transit Time (s), Perfusion Index (rBV/mTT), Wash-in Rate)

From: Reducing tumor growth and angiogenesis using a triple therapy measured with Contrast-enhanced ultrasound (CEUS)

  Whole tumor   Hypervascular area  
  Baseline   Follow-up   P Baseline   Follow-up   p
  Mean SD Mean SD   Mean SD Mean SD  
Therapy: relative Blood Volume 337.3 273 164.3 193.7 0.01 595.4 448.8 190.3 57.4 0.01
Control: relative Blood Volume 131.6 72 529.9 237.2 0.01 320.8 183.5 414.9 51.1 0.16
Therapy: mean Transit Time (s) 4.2 2.0 8.3 5.1 0.01 4.8 2.3 13.2 6.5 0.01
Control: mean Transit Time (s) 6.8 5.2 4.5 1.9 0.18 4.7 2.6 6.6 5.6 0.34
Therapy: Perfusion Index (rBV/mTT) 102.6 96 27.4 39.3 0.01 177.2 197.0 32.0 50.9 0.01
Control: Perfusion Index (rBV/mTT) 30.2 25 123.9 63.7 0.01 91.2 57.4 121.8 95.2 0.38
Therapy: Wash-in Rate 37.5 33 11.7 8.3 0.01 102.8 76.8 25.5 14.3 0.01
Control: Wash-in Rate 21.6 16 27.9 25.8 0.6 63.6 39.8 154.3 84.4 0.01