Therapy group : dark gray/Controll group : light gray. Subsequently, in the therapy group we observed a significant (p ≤ 0.01) decrease of the relative Blood Volume (rBV) between the baseline and follow-up measurements of the whole tumor (wt) (a) and of the hypervascular tumor (ht) areas (b) (p ≤ 0.01). The mean Transit Time (mTT) of the wt (c) and the ht (d) areas showed significant increase (p ≤ 0.003/0.001) in the follow-up measurements. In the control group, we observed a significant (p ≤ 0.01) increase of the rBV between the baseline and follow-up measurements of the wt and a minor increase (p ≤ 0.16) of the ht areas. The mTT of the wt and the ht areas showed no significant changes in the follow-up measurements.