Correlation of Aurora-A expression with the effect of chemoradiation therapy on esophageal squamous cell carcinoma

Table 3 Correlation of Aurora-A expression with histological and clinical responses to CRT in the surgical group of ESCC patients

	Histological response to CRT (n = 41)
	Grade1	Grade2	Grade3	Total	P
Aurora-A
(+)	7	8	9	24	0.003
( −)	13	4	0	17
Clinical response
CR	0	1	8	9	0.0001
IR/SD	17	11	1	29
PD	3	0	0	3

Grade 2 or 3 was judged as effective CRT and a response of Grade 1 was judged as ineffective CRT.
CR: Complete Response, complete disappearance of the primary lesion.
IR/SD: Incomplete Response/Stable Disease of the primary lesion.
PD: Progressive Disease, progressive disease of the primary lesion.
Aurora-A (+)/(−), Aurora-A positive/negative expression.

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