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Table 3 Correlation of Aurora-A expression with histological and clinical responses to CRT in the surgical group of ESCC patients

From: Correlation of Aurora-A expression with the effect of chemoradiation therapy on esophageal squamous cell carcinoma

  Histological response to CRT (n = 41)   
  Grade1 Grade2 Grade3 Total P
Aurora-A      
(+) 7 8 9 24 0.003
( −) 13 4 0 17  
Clinical response      
CR 0 1 8 9 0.0001
IR/SD 17 11 1 29  
PD 3 0 0 3  
  1. Grade 2 or 3 was judged as effective CRT and a response of Grade 1 was judged as ineffective CRT.
  2. CR: Complete Response, complete disappearance of the primary lesion.
  3. IR/SD: Incomplete Response/Stable Disease of the primary lesion.
  4. PD: Progressive Disease, progressive disease of the primary lesion.
  5. Aurora-A (+)/(−), Aurora-A positive/negative expression.