Figure 2

Disease-specific survival curves of ESCC patients treated with CRT and surgery according to Aurora-A expression. (A) Of 78 patients, the 2-year or 5-year survival rates of patients with Aurora-A (+) and Aurora-A (−) tumors were 49.0 and 28.1% or 29.5 and 28.1%, respectively (P = 0.08). (B) Of 78 patients, the 5-year survival rate of patients with CR and IR/SD, or with PD clinical responses to CRT were 46.0 and 27.3%, respectively (P = 0.02). (C) Of the 41 patients who underwent surgery, the 2-year or 5-year survival rates of patients with Aurora-A (+) and Aurora-A (−) tumors were 64.8 and 41.2 or 47.1and 40.2%, respectively (P = 0.3). (D) The 5-year survival rate of patients with grade 2 or 3, or with grade 1 tumors was 61.8 and 21.2%, respectively (P = 0.002). P-values were calculated using log-rank tests.