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Table 3 Fold changes and associated p-values for miR-34a, miR-150, and miR-923 in the validation cohort

From: Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression

  miR-34a miR-150 miR-923
  FC P value FC P value FC P value
Normal vs Polyp −1.3 0.286 1.52 0.218 1.24 0.537
Normal vs Adenoma 2.09 0.028 1.68 0.160 1.19 0.537
Normal vs Early Stage Cancer 2.84 0.002 −1.03 0.800 1.19 0.675
Normal vs Advanced Cancer 1.8 0.081 −1.52 0.282 −1.7 0.537
Polyp vs Adenoma 2.71 0.002 1.11 0.735 −1.04 0.904
Polyp vs Early Stage Cancer 3.69 0.000 −1.57 0.160 −1.05 0.779
Polyp vs Advanced Cancer 2.34 0.006 −2.31 0.007 −2.11 0.113
Adenoma vs Early Stage Cancer 1.36 0.381 −1.73 0.104 −1.01 0.867
Adenoma vs Advanced Cancer −1.16 0.691 −2.55 0.001 −2.03 0.113
Early Stage Cancer vs Advanced Cancer −1.58 0.169 −1.47 0.529 −2.02 0.113
Non-Cancer vs Early Stage Cancer 3.07 0.000 1.42 0.160 1.19 0.675
Non-Cancer vs Cancer 2.62 0.001 1.29 0.013 −1.11 0.779
Normal & Polyp vs Adenoma 1.9 0.002 1.98 0.282 1.08 0.537
  1. Bold text denotes significant comparisons. Non-Cancer comprises normal, polyp & adenoma groups, Cancer comprises both early stage & advanced cancer groups.